Role of the tumor-associated trypsin inhibitor SPINK1in cancer development

• 来源期刊: 亚洲男性学杂志（英文版）
• 年，卷（期）: 2011,（4）
• 页码范围: 628-629
• 页数: 2页
• 语种: 英文
• DOI: 10.1038/aja.2011.45

摘要

In most industrialized countries, prostate cancer is the most common non-skin cancer of men.When detected early, most cases are curable, but for tumors that have metastasized, there is no curative therapy.Pharmaceutical androgen ablation or castration induces remission in most patients with metastatic disease, but if the patient lives long enough, the tumor becomes androgen-independent.In some patients, chemotherapy induces remission, which mostly is of short duration.Therefore, new treatment modalities are needed for androgen-independent prostate cancer.