Common Movement Disorders in Children: Diagnosis, Pathogenesis and Management

• 作者: Isabelle Korn-Lubetzki Israel Steiner
• 来源期刊: 神经系统科学与医药(英文)
• 学科: 医学
• 关键词: MOVEMENT DISORDER CHILDREN
• 年，卷（期）: 2012,（1）
• 页码范围: 90-100
• 页数: 11页
• 分类号: R73

摘要

Movement disorders in childhood are a heterogeneous group of diseases with presentations that vary according to etiopathogenesis and age of onset. While sharing certain characteristics with the conditions that affect adults, they also have unique features that are determined by the metabolic, physiological and environmental distinctiveness of the developing brain. This context makes the nervous system of children vulnerable to various insults such as birth trauma, infections and toxicity. Some inborn errors of metabolism and genetic conditions selectively affect the young brain and psychological adaptation may also contribute to the occurrence and severity of certain conditions at this age group. The present review outlines the pathophysiology, clinical presentation and course, diagnosis and therapy of movement disorders in children. We also emphasize, when available, preventive and prophylactic measures and conclude by suggesting several avenues for future research in aspects that are currently not well understood.