Indirect calorimetry in obese female subjects:Factors influencing the resting metabolic rate

• 作者: Barbara Neri Cecilia Coletti Claudia Savina Eleonora Poggiogalle Lorenzo Maria Donini Luciano Scavone Maddalena Paolini Theresa Hagedorn
• 来源期刊: 世界实验医学杂志
• 学科: 医学
• 关键词: Indirect CALORIMETRY OBESITY RESTING METABOLIC rate RESTING energy EXPENDITURE
• 年，卷（期）: 2012,（3）
• 页码范围: 58-64
• 页数: 7页
• 分类号: R

摘要

energy expenditure(REE)in obese female subjects.METHODS:Seventy seven 61 obese Caucasian women[mean age of 52.93±13.45 years,and mean body mass index(BMI)of 41.78±11.54 kg/m2]were enrolled;measurements of resting metabolic rate(RMR)by a ventilated,open-circuit system,indirect calorimeter were performed after an overnight fast.Body composition as well as medications,physical parameters,blood samples,disease pattern,and smoking were considered.RESULTS:RMR was significantly associated with body weight(r=0.732,P<0.001),body height(r=0.401,P=0.008),BMI(r=0.504,P<0.001),waist circumference(r=0.602,P<0.001),mid-upper arm circumference(r=0.417,P=0.006),mid-upper arm muscle circumference(r=0.344,P=0.028),total body water(r=0.339,P=0.035),body temperature(r=0.409,P=0.007),smoking(P=0.031),serum T4 levels(r=0.331,P=0.036),obstructive sleep apnoea syndrome(OSAS;P=0.023),impaired glucose tolerance(IGT;P=0.017)and impaired glycaemic status,including hyperinsulinism,IGT and diabetes mellitus(P=0.003).CONCLUSION:Future research should be prompted to optimize the procedure of indirect calorimetry to achieve clinical benefits in obese subjects.