D-Aspartate, a Key Element for the Improvement of Sperm Quality

• 作者: Antimo D’Aniello Fara Mascia Gemma D’Aniello George Fisher Maria Maddalena Di Fiore Natascia Grieco Nicola D’Angel Salvatore Ronsini Tiziana Notari Vincenzo Infante
• 来源期刊: 性医学进展(英文)
• 学科: 医学
• 关键词: D-ASPARTATE Oligo-Asthenozoospermia ASTHENOZOOSPERMIA PREGNANCIES
• 年，卷（期）: 2012,（4）
• 页码范围: 45-53
• 页数: 9页
• 分类号: R73

摘要

Introduction: D-Aspartate is an endogenous amino acid involved in LH and testosterone release in humans. In this study we investigate the impact of nutritional supplementation of sodium D-aspartate on the improvement of sperm quality in sub-fertile patients and the rate of pregnancies that occurred with their partners. Materials and Methods: A group of 30 patients affected by oligo-asthenozoospermia and a group of 30 patients affected by asthenozoospermia were treated with a daily dose of sodium D-aspartate for 90 days. After which, the change in spermatozoa concentration and their motility and the pregnancies that occurred with their partners were recorded. Results: We found that the supplementation of D-aspartate significantly increased the concentration and the motility of spermatozoa. In oligo- asthenozoospermic patients the increase of sperm concentration was found to be 2.0-fold, P Conclusions:Treatment of sub-fertile patients with sodium D-aspartate improved the number and the motility of the spermatozoa and consequently improved the rate of pregnancies of their partners.