Self-eating with your fingers

• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2012,（5）
• 页码范围: 783-785
• 页数: 3页
• 语种: 英文
• DOI: 10.1038/cr.2012.39

摘要

BECN1 plays a central role in determining cell fate,acting as a balance point in the decision to undergo autophagy or apoptosis.Three distinct structural domains allow BECN1 to interact with several other proteins.Recent crystallographic data provide insight into the nature of the coiledcoil and evolutionarily conserved domains.