Use of antidepressants in diabetes patients not using drugs, but only monitoring blood glucose

• 作者: ?ivind Hundal Anders Lund Eva Biringer Inge Losnegard
• 来源期刊: 糖尿病(英文)
• 学科: 医学
• 关键词: Type 2 DIABETES METABOLIC Syndrome Blood GLUCOSE STRIPS Depression COMORBIDITY
• 年，卷（期）: 2012,（2）
• 页码范围: 234-237
• 页数: 4页
• 分类号: R73

摘要

Objective: Patients with diabetes have an increased Odds Ratio (OR) for depressive disor- der. We wanted to investigate if patients with metabolic syndrome and/or diabetes type 2 not treated with antidiabetic agents, have an OR for concurrent antidepressant use comparable to other types of diabetes. Methods: Drug delivery data from 25 pharmacies were analysed with respect to sale of antidepressants, oral antidiabetic agents, insulin and blood glucose test strips. Results: Total population of the area was 337,019, whereas 254,083 were 18 or older. Of these 20,139 were patients receiving insulin, oral antidiabetics, glucose test strips and/or antidepressants. Those receiving antidepressants were 5.8% of those 18 or older whereas 2.4% received any antidiabetic medication (including test strips for HBGM). For patients receiving no medications but test strips alone, the adjusted OR for use concurrent use of antidepressants was 1.62 (95% confidence interval: 1.19 - 2.23), p = 0.002. For insulin-only receiving patients, the adjusted OR was 1.65 (1.41 - 1.93), p = 0.000, whereas for patients receiving only oral antidiabetics, it was 1.53 (1.38 - 1.71), p = 0.000. Patients receiving both insulin and oral antidiabetics: 2.23 (1.75 - 2.85), p = 0.000. Conclusion: Patients receiving only blood glucose strips have an OR of concurrently receiving antidepressants, not different from those receiving insulin only or oral antidiabetics only.