在动脉粥样硬化患者匾成像进行

• 作者: Giulia Soloperto Sergio Casciaro
• 来源期刊: 世界放射学杂志：英文版（电子版）
• 学科: 医学
• 关键词: ATHEROSCLEROSIS DIAGNOSTIC IMAGING PLAQUE CHARACTERIZATION
• 年，卷（期）: 2012,（8）
• 页码范围: 353-371
• 页数: 19页
• 分类号: R543.5

摘要

Cardiovascular diseases are the primary cause of mortality in the industrialized world,and arterial obstruction, triggered by rupture-prone atherosclerotic plaques,lead to myocardial infarction and cerebral stroke.Vulnerable plaques do not necessarily occur with flow-limiting stenosis,thus conventional luminographic assessment of the pathology fails to identify unstable lesions.In this review we discuss the currently available imaging modalities used to investigate morphological features and biological characteristics of the atherosclerotic plaque. The different imaging modalities such as ultrasound, magnetic resonance imaging,computed tomography, nuclear imaging and their intravascular applications are illustrated,highlighting their specific diagnostic potential.Clinically available and upcoming methodologies are also reviewed along with the related challenges in their clinical translation,concerning the specific invasiveness, accuracy and cost-effectiveness of these methods.