Syntheses and Crystal Structures of 3-Chloro-N＇-（3,5-dichloro-2-hydroxybenzylidene）-benzohydrazide and Its Oxovanadium（V） Complex with Antimicrobial Activity

• 作者: GAO Shuan-Ping
• 来源期刊: 结构化学
• 学科: 农学
• 关键词: 抗菌活性 羟苯基 氯基 晶体结构 氧钒 配合物 单晶X-射线衍射 金黄色葡萄球菌
• 年，卷（期）: 2012,（3）
• 页码范围: 377-384
• 页数: 8页
• 分类号: O614.121|S859.796
• 语种: 英文

摘要

A hydrazone compound 3-chloro-N＇-（3,5-dichloro-2-hydroxybenzylidene）benzo-hydrazide（H2L） derived from the condensation of 3,5-dichlorosalicylaldehyde with 3-chloro-benzohydrazide and its oxovanadium（V） complex [VOL（CH3OH）（OCH3）] have been successfully prepared and characterized by physico-chemical methods and single-crystal X-ray diffraction.The hydrazone ligand coordinates to the V atom through the phenolate O,imine N,and enolic O atoms.The V atom is hexa-coordinated in a distorted octahedral geometry.The antimicrobial activities（MIC） of the hydrazone ligand and the oxovanadium（V） complex have been evaluated against the bacteria Staphylococcus aureus,Baccilus subtilis,Pseudomonas aeruginosa,and Escherichia coli.