Efficient synthesis of functionalized 2-pyridones by ytterbium chloride catalyzed tandem condensation

• 来源期刊: 科学通报(英文版)
• 学科: 化学
• 年，卷（期）: 2012,（14）
• 页码范围: 1612-1615
• 页数: 4页
• 分类号: O626
• 语种: 中文

摘要

An efficient method was developed for the synthesis of arylidene heterobicyclic 3-cyano-2-pyridones via ytterbium chloride catalyzed tandem condensation of aromatic aldehydes,cyclic ketones,and cyanoacetamide.The conditions and scope of the reaction were investigated and a reaction mechanism was proposed.