Carbon Paste Electrode Prepared from Chemically Modified Multiwall Carbon Nanotubes for the Voltammetric Determination of Isoprenaline in Pharmaceutical and Urine Samples

• 作者: 0Hassan KARIMI-MALEH Ali A. ENSAFI* Hajar BAHRAMI Shadpour MALLAKPOUR
• 来源期刊: 催化学报
• 关键词: isoprenaline carbon nanotube electrode electrocatalytic effect voltammetry
• 年，卷（期）: 2012,（12）
• 页码范围: 1919-1926
• 语种: 中文
• DOI: 10.1016/S1872-2067(11)60465-8

摘要

A carbon paste electrode with added multiwall carbon nanotubes chemically modified with N-(3,4-dihydroxyphenethyl)-3,5-dinitrobenzamide was used as the electrochemical sensor for the determination of trace amounts of isoprenaline. The modified electrode showed good electrocatalytic activity for the anodic oxidation of isoprenaline, which was due to a substantial decrease in the anodic overpo-tential. Under the optimum conditions, measurements using square wave voltammetry had a linear range in the range of 0.3 to 125.0μmol/L of isoprenaline and a detection limit of 0.1μmol/L. The diffusion coefficient and kinetic parameters were determined using electrochemical methods. The relative standard deviation for seven successive assays of 1.0 and 20.0μmol/L isoprenaline were 1.9% and 2.4%, respectively. This electrochemical sensor was successfully applied for the determination of isoprenaline in human urine and injection solution samples.