Microwave-assisted Syntheses and Crystal Structures of Benzimidazole Thiazolinone Derivatives

• 作者: HU Jun WANG Ji-Kui WANG Peng XU Yan-Hua
• 来源期刊: 结构化学
• 学科: 化学
• 关键词: 苯并咪唑类 微波辅助合成 晶体结构 酮衍生物 噻唑啉 X-射线衍射 氢键相互作用 合成方法
• 年，卷（期）: 2012,（12）
• 页码范围: 1745-1751
• 页数: 7页
• 分类号: O614.121|TQ463.53
• 语种: 英文

摘要

A rapid and efficient microwave-assisted synthesis method for the preparation of 3-(lH-benzo[d]imidazol-2-yl)-2-substituted phenyl thiazolidin-4-one (4a, 4b) was described. The structures of 4a and 4b were determined by elemental analyses, IR, 1H NMR and X-ray diffraction. In the crystals of compounds 4a and 4b, the imidazole ring and two benzene rings are planar. Interestingly, the dihedral angle between two benzene rings is 71.5° in 4a, while it is almost perpendicular in 4b due to the different benzene substituents. Meanwhile, the thiazolidinone ring is planar in 4a while slightly distorted with an r.m.s deviation of 0.1494(2) A in 4b. The hydrogen bonding interactions observed link the molecules to form a dimeric unit, which may be effective in the stabilization of the structure.

作者信息

序号	姓名	单位	发文数	被引次数	H指数	G指数
1	HU Jun		1	0	0.0	0.0
2	WANG Peng		1	0	0.0	0.0
3	WANG Ji-Kui		1	0	0.0	0.0
4	XU Yan-Hua		1	0	0.0	0.0