Application of Amino-Functionalized SBA-15 Type Mesoporous Silica in One-Pot Synthesis of Spirooxindoles

• 作者: Afsaneh SHAHBAZI Alireza BADIEI Ghodsi MOHAMMADI ZIARANI Negar LASHGARI Somayeh MOUSAVI
• 来源期刊: 催化学报
• 学科: 化学
• 关键词: amino-functionalized SBA-15 spirooxindoles isatin nano-reactor green synthesis
• 年，卷（期）: 2012,（11）
• 页码范围: 1832-1839
• 分类号: O643
• 语种: 中文
• DOI: 10.1016/S1872-2067(11)60456-7

摘要

Amino-functionalized SBA-15(SBA-Pr-NH2) has been used as a new basic nanocatalyst in the one-pot synthesis of spirooxindole derivatives via the three-component condensation reaction of isatins, activated methylene reagents, and dimedone in an aqueous medium. SBA-Pr-NH2 has been established as an efficient heterogeneous nanoporous solid basic catalyst (pore size of 6 nm) that can be easily handled and removed from the reaction mixture by simple filtration, and also recovered and reused without noticeable loss of reactivity.