BACKGROUND:With the extensive development of the renal transplants from living-related donors, how to protect the donors’ long-term survival get more and more attention. OBJECTIVE:To summarize our clinical experience of 79 potential living-related kidney donors, and to evaluate the effects and reliability of the procedure. METHODS:We analyzed clinical data from 79 potential living-related kidney donors assessed at the Department of Transplantation and Urology, Affiliated Ruikang Hospital of Guangxi University of Chinese Medicine from June 2007 to August 2010. And the clinical effect was analyzed. RESULTS AND CONCLUSION:A total of 38 patients were assessed for qualified. The operating time for al donors ranged from 1 to 2 hours. The warm ischemia time of the donated kidney was about 15 seconds, and the cold ischemia time was 1-2 hours. No surgical or medical complications occurred during the perioperative period. Al donors have survived to date, with kidney function in the normal range. Rigorous assessment is important for ensuring the long-term survival of living kidney donors.