Intra-abdominal drains are still routinely used in the surgical management of gangrenous and perforated appendicitis.A systematic review was performed with the aim of establishing their influence on postoperative complications in such cases.A literature search was conducted using the search engines PubMed and Cochrance Central Register of Controlled Trials.Included were retrospective case-controlled and prospective randomized controlled trials on the use of drain for open appendicectomy in gangrenous and perforated appendicitis.Twelve articles were found that met the inclusion criteria.Intrabdominal abscesses,postoperative ileus,surgical site infections,fecal fistulas and burst abdomen had significant higher incidences in the drain vs non drain group(10.3%,20.3%,32.5%,3.4%and 5.7%vs 4.7%,8.5%,16.2%,0%and 0%,respectively).In most cases the risk was more than doubled in the drain group compared to the non-drain one.There were no significant differences among groups in terms of mortality while the results were underpowered to effectively evaluate wound dehiscence and adhesions.The use of intra-abdominal drains in the management of gangrenous and perforated appendicitis by open appendicectomy is associated with an increased rate of common postoperative complications.