Recent Advances in Detection of Ochratoxin-A

• 作者: Abhay Vasudev Ajeet Kaushik Shekhar Bhansali Sunil K. Arya
• 来源期刊: 生物传感器(英文)
• 学科: 医学
• 关键词: BIOPOLYMER Mycotoxins Ochratoxin-A CHITOSAN ORGANIC-INORGANIC HYBRID NANOCOMPOSITE Biosensors
• 年，卷（期）: 2013,（1）
• 页码范围: 1-11
• 页数: 11页
• 分类号: R73

摘要

Ochratoxin-A[7-(L-β-phenylalanylcarbonyl)-carboxyl-5-chloro-8-hydroxy-3,4-dihydro-3R-methyl-isocumarin, OTA] is a common food contaminant mycotoxin that enters the human body through the consumption of improperly stored food products. Upon ingestion, it leads to immuno-suppression and immuno-toxicity. OTA has been known to produce nephrotoxic, teratogenic, and carcinogenic activity (via oxidative DNA damage) in several species. This review introduces potentials of electrochemical biosensor to provide breakthroughs in OTA detection through improved selectivity and sensitivity and also the current approaches for detecting OTA in food products.