Electrochemical Bioencapsulation of Nanomaterials into Collagen for Biomedical Applications

• 作者: Christopher Tsao Lauren Cornell Thomas Potter Vasiliki Poenitzsch Xingguo Cheng
• 来源期刊: 封装与吸附期刊(英文)
• 学科: 化学
• 关键词: NANOMATERIALS ELECTROCHEMICAL BIOENCAPSULATION COLLAGEN BIOMEDICAL APPLICATIONS
• 年，卷（期）: 2013,（1）
• 页码范围: 16-23
• 页数: 8页
• 分类号: O6

摘要

Here we reported a novel electrochemical encapsulation method to encapsulate various nanomaterials and bimolecules into collagen. The electrochemical encapsulation process involves assembling of collagen along with Nano/bio materials using an isoelectric focusing mechanism. We have showed that a wide range of Nanomaterials such as carbon nanotubes, polymeric nanoparticles, magnetic calcium phosphate nanoparticles?and biomolecules can be encapsulated into collagen. These novel collagen-based composite materials possess improved electric, mechanical, antimicrobial, magnetic, bioactive properties. Thus, this novel electrochemical encapsulation process offers a means to fabricate novel biomaterials for various biomedical applications such as tendon/ligament, nerve, skin tissue engineering, tendon/ligament to bone grafts, and sutures, etc.