Investigation of Tissue Thermal Damage Process with Application of Direct Sensitivity Method

• 作者: Marek Jasinski
• 来源期刊: 分子与细胞生物力学(英文)
• 学科: 工学
• 关键词: bioheat transfer TISSUE INJURY INTEGRAL sensitivity analysis BOUNDARY ELEMENT METHOD
• 年，卷（期）: 2013,（3）
• 页码范围: 183-199
• 页数: 17页
• 分类号: TG1

摘要

In the paper the numerical analysis of thermal processes proceeding in the biological tissue is presented.The tissue is subjected to the external heat flux and 2D problem is taken into account.In order to determine the influence of variations of thermophysical parameters of tissue on the value of Arrhenius injury integral the direct approach of sensitivity analysis is applied.On the basis of tissue damage fraction the thermal injury formation process is analysed.At the stage of numerical realization the boundary element method is used.In the final part of the paper the example of numerical simulation is shown.