Mechanisms of Action of Noninvasive Monopolar Radiofrequency: Technology Review

• 作者: Scott P. Steinmann Terry L. Whipple
• 来源期刊: 矫形学期刊(英文)
• 学科: 医学
• 关键词: Thermal Shrinkage Thermoplasty HEAT-SHOCK AT2 RADIOFREQUENCY Collagen DENATURATION Tendinosis Wound Healing Response TENDINOPATHY Microtenotomy ANTINOCICEPTIVE
• 年，卷（期）: 2013,（1）
• 页码范围: 23-28
• 页数: 6页
• 分类号: R73

摘要

Tendinosis is now understood as the result of a failed tendon healing process regardless of where it occurs in the body. Current noninvasive therapeutic alternatives are anti-inflammatory in nature and outcomes are unpredictable at best. The benefit of invasive alternatives resides in the induction of the healing response as demonstrated in pre-clinical and clinical studies in cardiology and orthopaedics. A new technology that employs noninvasivemonopolar capacitive-coupled radiofrequency (mcRF), has demonstrated the ability to raise temperatures in tendons and ligaments upwards of 50°C, the temperature threshold for collagen modulation and recruitment of macrophages, fibroblasts and Heat Shock Protein factors—without damaging the overlying structures—resulting in activation of the Wound Healing Response (WHR).