Molecularly Imprinted Micro-Solid-Phase Extraction for the Selective Determination of Phenolic Compounds in Environmental Water Samples with High Performance Liquid Chromatraphy

• 作者: Diandou Xu Liyuan Liu Qinzhong Feng Yang Chen Zhengjie Zhang
• 来源期刊: 高分子化学期刊(英文)
• 学科: 化学
• 关键词: SUSPENSION Polymerization Molecularly Imprinted Micro-Solid-Phase Extraction 2 4 6-Trichlorophenol PHENOLIC Compounds High Performance LIQUID Chromatography
• 年，卷（期）: 2013,（3）
• 页码范围: 54-62
• 页数: 9页
• 分类号: O6

摘要

2,4,6-trichlorophenol molecularly imprinted suspension polymer has been prepared and applied to the molecularly imprinted micro-solid-phase extraction procedure for selective preconcentration of phenolic compounds from environmental water samples. The influence of functional monomer, cross-linker, polymerization condition, porogen, and the ratio of template molecule and functional monomer to cross-linker on the size of the obtained particles were investigated. It was found that methyacrylic acid as functional monomer, divinylbenzene as cross-linker, the molar ratio of template molecule and functional monomer to cross-linker was 1:4:20, the amount of AIBN was 100 mg, ultraviolet radiation at 365 nm were the optimal conditions, and at these conditions, the polymers had the best adsorption efficiency and had the monodispersity of 2 - 3 μm microsphere particles. The characteristics of the MIMSPE method were valid by high performance liquid chromatography. This MIMSPE-HPLC method has been successfully applied to the direct preconcentration and determination of phenolic compounds (phenol, 4-chlorophenol, 2,4-dichlorophenol, 2,4,6-trichlorophenol, pentachlorophenol) in environmental water samples.