Remission of arthritis but persistent cutaneous lesions following tocilizumab treatment in a RA-patient suffering from concomitant psoriasis

• 作者: Boris Ehrenstein Martin Fleck Rotraud Wallisch Wolfgang Hartung
• 来源期刊: 临床医学病理报告(英文)
• 学科: 医学
• 关键词: TOCILIZUMAB Rheumatoid ARTHRITIS PSORIASIS TREATMENT
• 年，卷（期）: 2013,（1）
• 页码范围: 63-65
• 页数: 3页
• 分类号: R5

摘要

Modulation of the interleukin-6 pathway with tocilizumab has been demonstrated to be highly effective in substantial numbers of patients suffering from rheumatoid arthritis (RA), and juvenile idiopathic arthritis. A pivotal role of the IL-6 pathway has been also established in other autoimmune conditions including psoriasis and psoriatic arthritis, becoming attractive targets for therapeutic IL-6 inhibition. Here, we describe the first case of tocilizumab treatment in a RA-patient suffering from concomitant severe psoriasis, who achieved remission of RA, whereas no improvement of psoriatic lesions could be observed.