The Use of Dried Blood Spot Samples in Screening Drugs of Abuse

• 作者: Atul Ambekar Raka Jain Rizwana Quraishi
• 来源期刊: 药理与制药(英文)
• 学科: 医学
• 关键词: DRIED Blood SPOTS DRUGS of ABUSE SCREENING Review
• 年，卷（期）: 2013,（2）
• 页码范围: 152-159
• 页数: 8页
• 分类号: R73

摘要

The present article will provide an overview of use of dried blood sampling method for analysis of drug of abuse. Relatively short half life and instability in blood, calls for alternative sampling method for determination of drugs of abuse. Dried blood spot (DBS) method has many advantages over the conventional sampling methods. The available method for DBS sample collection, storage and transport are described here. The techniques involved in and the factors that may influence the accuracy and reproducibility of the DBS methods for determination of drugs of abuse are presented. The DBS sampling has the potential to be a useful technique to detect drugs of abuse. The use of DBS for any drug should be judged against the potential error involved with the method.