Diabetic mouse models

• 作者: Masami Shinohara Takahisa Yamada Takeshi Ohta Tong Bin Yoshiaki Katsuda
• 来源期刊: 动物科学期刊(英文)
• 学科: 医学
• 关键词: DIABETES DIABETIC COMPLICATION MOUSE MODEL OBESITY
• 年，卷（期）: 2013,（4）
• 页码范围: 334-342
• 页数: 9页
• 分类号: R58

摘要

The number of patients with lifestyle-related diseases, such as cardiovascular disease, diabetes mellitus, hypertension, atherosclerosis, and cancer, is increasing all over the world, and that of diabetics is increasing especially rapidly. Diabetic animal models have played a key role in elucidating the etiology of diabetes and developing anti-diabetic drugs. In this review, we overviewed characteristics of diabetic mouse models and pharmacological evaluation using the diabetic models.