Optimization of Contrast Material Dose for Abdominal Multi-Detector Row CT: Predicting Patient Lean Body Weight by Using Preliminary Transverse CT Images

• 作者: Antonino Guerrisi Carlo Catalano Daniele Marin Huiman Barnhart Lisa Ho Rendon C. Nelson Thomas L. Toth
• 来源期刊: 计算机断层扫描(英文)
• 学科: 医学
• 关键词: LEAN Body WEIGHT Multi-Detector CT CONTRAST DOSE
• 年，卷（期）: 2014,（1）
• 页码范围: 1-10
• 页数: 10页
• 分类号: R73

摘要

Estimated LBW could be used to determine the contrast material dose and rate during MDCT. The aim of this study is to test the accuracy of a technique for estimation of lean body weight (LBW) from a single multi-detector row computed tomographic (MDCT) abdominal image, using a bioelectrical body composition analyzer scale as the reference standard. CT images of 21 patients with previously measured LBW (mLBW) were processed using computer-assisted, vendor-specific software (Advantage Windows 4.2;GE Healthcare, Inc). For each transverse image, a fat-fraction was automatically measured as the number of fat pixels (-200 to -50 HU) divided by the total number of pixels having an attenuation value ≥-200 HU. Estimated LBW (eLBW) of five single contiguous sections was calculated in each of three abdominal regions (upper abdomen, mid abdomen and pelvis) by multiplying TBW by (1 – fat-fraction). Bland-Altman plot with limits of agreement was used to assess agreement between mLBW and eLBW. The mean mLBW for all patients was 56 kg (range, 39 - 75 kg). Mean differences and limits of agreement between mLBW and eLBW measurements for the upper abdomen, mid abdomen and pelvis reported were -8.9 kg (-25.6 kg, +7.5 kg), -10.6 kg (-27.7 kg, +6.4 kg), and +0.5 kg (-12.8 kg, +13.8 kg) respectively. eLBW deriving directly from a transverse CT image of the pelvis can accurately predict mLBW.