Solitary pituitary metastasis resulting from pulmonary large cell neuroendocrine carcinoma

• 作者: Kyoichi Kaira Masafumi Mizuide Masanobu Yamada Masatomo Mori Nobuyuki Shibusawa Noriaki Sunaga Takeshi Hisada Takuya Watanabe Tetsurou Satoh
• 来源期刊: 世界呼吸病学杂志
• 学科: 医学
• 关键词: Large cell NEUROENDOCRINE carcinoma PITUITARY METASTASIS SOLITARY ENDOCRINOPATHY
• 年，卷（期）: 2014,（1）
• 页码范围: 8-10
• 页数: 3页
• 分类号: R

摘要

Solitary pituitary metastasis is a rare phenomenon in human neoplasms.We report a case of lung cancer with the initial manifestation of endocrinopathy resulting from pituitary metastasis.The patient’s initial diagnosis was a poorly differentiated carcinoma,however,morbid anatomy revealed a definite diagnosis of large cell neuroendocrine carcinoma(LCNEC).Clinical physicians should be aware of potential initial manifestations such as endocrine abnormalities including panhypopituitarism and diabetes insipidus due to solitary pituitary metastasis.This case demonstrates that an endocrine abnormality such as panhypopituitarism could be an initial manifestation of LCNEC.