基本信息来源于合作网站,原文需代理用户跳转至来源网站获取       
摘要:
Radiation therapy is a key weapon in the modern arsenal of cancer treatment. However, this effective treatment comes with risks of its own, and the sheer number of patients that undergo radiation as a part of their therapy regimen is only increasing. As this number increases, so does the incidence of secondary, radiation-induced neoplasias, creating a need for therapeutic agents targeted specifically towards reduction in the incidence of and treatment of these cancers. Development and efficacy testing of these agents requires not only extensive?in vitro?testing, but also a set of reliable animal models to accurately recreate the complex situations of radiation-induced carcinogenesis. The laboratory mouse?Mus musculus?remains the most relevant animal model in cancer research due to the molecular and physiological similarities it shares with man, its small size and high rate of breeding in captivity, and its fully sequenced genome. In this work, we review relevant?M. musculusinbred and?F1?hybrid animal models, as well as methods of induction of radiation-induced lung cancers. Associated molecular pathologies are also included.
内容分析
关键词云
关键词热度
相关文献总数  
(/次)
(/年)
文献信息
篇名 Radiation-Induced Lung Cancers in Murine Models
来源期刊 肺癌(英文) 学科 医学
关键词 RADIATION CARCINOGENESIS Animal Models RADIATION Protectors RADIATION Mitigators SECONDARY CANCERS
年,卷(期) 2014,(2) 所属期刊栏目
研究方向 页码范围 38-44
页数 7页 分类号 R73
字数 语种
DOI
五维指标
传播情况
(/次)
(/年)
引文网络
引文网络
二级参考文献  (0)
共引文献  (0)
参考文献  (0)
节点文献
引证文献  (0)
同被引文献  (0)
二级引证文献  (0)
2014(0)
  • 参考文献(0)
  • 二级参考文献(0)
  • 引证文献(0)
  • 二级引证文献(0)
研究主题发展历程
节点文献
RADIATION
CARCINOGENESIS
Animal
Models
RADIATION
Protectors
RADIATION
Mitigators
SECONDARY
CANCERS
研究起点
研究来源
研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
肺癌(英文)
季刊
2169-2718
武汉市江夏区汤逊湖北路38号光谷总部空间
出版文献量(篇)
44
总下载数(次)
0
总被引数(次)
0
论文1v1指导