为胰腺的 ductal 腺癌的客观描述与量的灌注分析对比提高的超声: 可行性研究

• 作者: Mirko D’Onofrio Riccardo De Robertis Roberto Pozzi Mucelli Stefano Canestrini Stefano Crosara
• 来源期刊: 世界放射学杂志：英文版（电子版）
• 学科: 医学
• 关键词: CONTRAST enhanced ULTRASOUND PANCREATIC ADENOCARCINOMA PERFUSION analysis Quantitative imaging
• 年，卷（期）: sjfsxzzywbdzb_2014,（3）
• 页码范围: 31-35
• 页数: 5页
• 分类号: R735.9

摘要

The aim of this study was to determine whether contrast enhanced ultrasound(CEUS) quantitative perfusion analysis allows an objective characterization of ductal adenocarcinoma(ADK) of the pancreas. Patients with pancreatic ADK underwent CEUS. All examinations were performed on an Acuson S2000 system(Siemens, Erlangen, Germany) after the iv administration of 2.4 mL contrast agent(SonoVue, Bracco, Milan, Italy). All lesions were pathologically proved. An operator manu-ally drew different regions of interest within the tumor and the adjacent parenchyma to allow the quantita-tive perfusion analysis. The mean values of peak of enhancement, time to peak and ascending curve were calculated and compared using the Student’s t test. The quantitative perfusion analysis was possible in all lesions. The mean values of the peak of enhancement, time to peak and ascending curve were 17.19%, 7.97 s and 159.52% s within the tumor and 33.57%, 8.89 s and 355.29% s within the adjacent parenchyma. The peak of enhancement and the ascending curve values were significantly different within the tumor and the ad-jacent parenchyma. Thus, CEUS allows the quantitative perfusion analysis of pancreatic ductal adenocarcinoma.