Epithelial ovarian cancer:An overview

• 作者: Anachebe Ngozi Arpita Desai Avinash Reddy Candace Gates Charles Landen Chika Okoli E Shyam P Reddy Edward E Partridge Geary Franklin Guilherme Cantuaria Jingyao Xu Karan Singh Kartik Aysola Omar Danner Ravipati Hariprasad Ugorji Chinemerem Valerie Montgomery Rice Veena N Rao William Grizzle Yunlong Qin
• 来源期刊: 世界转化医学杂志
• 学科: 医学
• 关键词: EPITHELIAL OVARIAN CANCER BREAST CANCER type 1 CHEMOTHERAPY
• 年，卷（期）: sjzhyxzz_2014,（1）
• 页码范围: 1-8
• 页数: 8页
• 分类号: R

摘要

Ovarian cancer is the second most common gynecological cancer and the leading cause of death in the United States.In this article we review the diagnosis and current management of epithelial ovarian cancer which accounts for over 95 percent of the ovarian malignancies.We will present various theories about the potential origin of ovarian malignancies.We will discuss the genetic anomalies and syndromes that may cause ovarian cancers with emphasis on Breast cancer type 1/2 mutations.The pathology and pathogenesis of ovarian carcinoma will also be presented.Lastly,we provide a comprehensive overview of treatment strategies and staging of ovarian cancer,conclusions and future directions.