Observation of Atherosclerotic Plaque Phantoms through Saline or Blood Layers by Near-Infrared Hyperspectral Imaging

• 作者: Akiko Kitayabu Katsunori Ishii Kunio Awazu Ryo Nagao
• 来源期刊: 光学与光子学期刊(英文)
• 学科: 医学
• 关键词: HYPERSPECTRAL Imaging NEAR-INFRARED Range ATHEROSCLEROTIC PLAQUE Angioscopy
• 年，卷（期）: 2014,（10）
• 页码范围: 271-279
• 页数: 9页
• 分类号: R73

摘要

We observed atherosclerotic plaque phantoms using a novel near-infrared (NIR) hyperspectral imaging (HSI) technique. Data were obtained through saline or blood layers to simulate an angioscopic environment for the phantom. For the study, we developed a NIR-HSI system with an NIR supercontinuum light source and mercury-cadmium-telluride camera. Apparent spectral absorbance was obtained at wavelengths of 1150 - 2400 nm. Hyperspectral images of lipid were constructed using a spectral angle mapper algorithm. Bovine fat covered with saline or blood was observed using hyperspectral images at a wavelength around 1200 nm. Our results show that NIR-HSI is a promising angioscopic technique with the potential to identify lipid-rich plaques without clamping and saline injection.