Snail and Slug mediate tamoxifen resistance in breast cancer cells through activation of EGFR-ERK independent of epithelial-mesenchymal transition

• 来源期刊: 分子细胞生物学报（英文版）
• 年，卷（期）: 2014,（4）
• 页码范围: 352-354
• 页数: 3页
• 语种: 中文
• DOI: 10.1093/jmcb/mju019

摘要

Dear Editor, Breast cancer is the second most common type of cancer and the leading cause of cancer death in women worldwide.Adjuvant tamoxifen therapy significantly slows down estrogen receptor (ER)-positive breast cancer progression,prolongs diseasefree survival,and contributes to the decrease in breast cancer mortality (Musgrove and Sutherland,2009).