Intraoperative perfusion magnetic resonance imaging: Cutting-edge improvement in neurosurgical procedures

• 作者: Stephan Ulmer
• 来源期刊: 世界放射学杂志：英文版（电子版）
• 学科: 医学
• 关键词: INTRAOPERATIVE MAGNETIC RESONANCE IMAGING DYNAMIC susceptibility CONTRAST MAGNETIC RESONANCE IMAGING DYNAMIC CONTRAST enhanced MAGNETIC RESONANCE IMAGING Surgically induced CONTRAST enhancement Neurosurgery
• 年，卷（期）: 2014,（8）
• 页码范围: 538-543
• 页数: 6页
• 分类号: R651.3

摘要

The goal in brain tumor surgery is to remove the maxi-mum achievable amount of the tumor, preventing damage to 'eloquent' brain regions as the amount of brain tumor resection is one of the prognostic factors for time to tumor progression and median survival. To achieve this goal, a variety of technical advances have been in-troduced, including an operating microscope in the late 1950 s, computer-assisted devices for surgical navigation and more recently, intraoperative imaging to incorporate and correct for brain shift during the resection of the lesion. However, surgically induced contrast enhancement along the rim of the resection cavity hampers interpretation of these intraoperatively acquired magnetic resonance images. To overcome this uncertainty, perfusion techniques [dynamic contrast enhanced magnetic resonance imaging(DCE-MRI), dynamic susceptibility contrast magnetic resonance imaging(DSC-MRI)] have been introduced that can differentiate residual tumor from surgically induced changes at the rim of the resec-tion cavity and thus overcome this remaining uncer-tainty of intraoperative MRI in high grade brain tumor resection.