MicroRNA-155 broadly orchestrates inflammation-induced changes of microRNA expression in breast cancer

• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2014,（2）
• 页码范围: 254-257
• 页数: 4页
• 语种: 英文
• DOI: 10.1038/cr.2013.137

摘要

Dear Editor, During the last decades,a number of key mediators of inflammation-induced tumorigenesis have been identified to support tumor progression in response to inflammation stimulation [1].Recent studies show that a few cancerrelated microRNAs (miRNAs) are modulated by inflammation signals [2,3],implicating miRNAs as a new class of mediators between inflammation and cancer.However,how inflammation regulates miRNAs in cancer cells and how such miRNA mediators function in inflammationassociated tumorigenesis remain largely unexplored.miRNA-155 (miR-155) has been documented as one of the most prominent miRNAs linking inflammation to cancer [4].