Presence of Illicit Drugs in the Sarno River (Campania Region, Italy)

• 作者: Anna Capaldo Ettore Zuccato Flaminia Gay Marco Guida Maria De Falco Massimo Maddaloni Salvatore Valiante Sara Castiglioni Vincenza Laforgia
• 来源期刊: 药理与制药(英文)
• 学科: 医学
• 关键词: CAMPANIA REGION COCAINE POLLUTION Environmental ILLICIT Drugs Sarno RIVER POLLUTION Surface Water POLLUTION
• 年，卷（期）: 2014,（7）
• 页码范围: 755-761
• 页数: 7页
• 分类号: R73

摘要

The presence of illicit drugs and their metabolites in surface waters has to be considered a new type of hazard, still unknown, for both the human health and the aquatic ecosystem, due to the potent pharmacological activities of all the illicit drugs. Our research was aimed at evaluating the presence of illicit drugs in the Sarno River (Campania region, Italy), crossing a densely populated area, the basin of the Sarno River, one of the largest and most important economic areas in Campania region, famous for the presence of zones with high landscape-environmental value. The drugs selected for this study were the most used in Campania region. The presence of illicit drugs in surface water was analyzed by a selective multi-residue assay based on liquid chromatographytandem mass spectrometry. The analysis showed the presence of all the illicit drugs investigated: cocaine and its main metabolites (benzoylecgonine, nor-benzoylecgonine), morphine, THC-COOH and codeine;cocaine was the most abundant illicit drug. The presence of illicit drugs and their metabolites in the Sarno River suggests new potential risk for the basin’s inhabitants, using water in the food chain, via field irrigation and animal feed, and for the health of the aquatic fauna.