During the past year, biophysics group at Institute of Modern Physics (IMP) obtained lots of achievements in theresearch of heavy-ion mutation breeding and production chain of sweet sorghum. In fundamental research field, amutant population of Arabidopsis thaliana induced by carbon ion beam radiation was established in M2 generation.The total mutation rate was 4.77%. A mutant marked 197#, which had frostbite-like, pale green, wrinkled anduneven leaves and displayed loose bracts and late maturation, was obtained and reported for the first time. Generough mapping results demonstrated that there were two mutation sites in the 1st and 4th chromosome of 197#mutant, indicating heavy ion radiation might induce more complicated mutations beyond our current recognition.The whole genome resequencing of this mutant is still in progress. In addition, high-yield strains of microbeswhich have potential value for commercial application, such as Corynebacterium glutamicum and Lacbobacillusthermophiles, were screened using heavy-ion mutation technique.