Mixed messages: Re-initiation factors regulate translation

• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2014,（12）
• 页码范围: 1383-1384
• 页数: 2页
• 语种: 中文
• DOI: 10.1038/cr.2014.114

摘要

When ribosomes encounter upstream open reading frames (uORFs)during scanning of the 5' untranslated region (5' UTR),translation of the downstream ORF requires re-initiation.In a recent paper in Nature,Schleich et al.describe metazoan factors which specifically promote re-initiation.