Backseat drivers: Regulation of dynein motility

• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2014,（12）
• 页码范围: 1385-1386
• 页数: 2页
• 语种: 中文
• DOI: 10.1038/cr.2014.115

摘要

Control of the activity of the microtubule motor cytoplasmic dynein 1 is essential for its function in intracellular transport.A recent paper by McKenney et al.published in Science shows that activation of processive dynein motility requires the formation of cargo adaptor-dynein-dynactin complexes.