摘要:
目的:观察飞秒激光制瓣 LASIK 术后不同性别泪膜的变化。<br> 方法:收集2013-08/09于我院行飞秒激光制瓣LASIK术并随访3mo的患者120例240眼,将其按性别分为两组,A组:男55例110眼,B组:女65例130眼,观察两组术前、术后1 wk;1,2,3 mo患者的干眼症状评分、泪膜破裂时间( break-up tear time, BUT )、泪液分泌试验( Schirmer Ⅰtest,SⅠt )、角膜荧光素染色( corneal fluorescence stain, FL)评分的变化。<br> 结果:主观干眼症状评分:两组术后1 wk;1,2 mo差异有统计学意义(P=0.000,0.023,0.030),术后3mo差异无统计学意义( P=0.283)。BUT:两组术后1 wk;1,2,3 mo差异有统计学意义( P=0.000,0.017,0.026,0.032)。SⅠt:两组术后1 wk;1,2 mo差异有统计学意义( P=0.012,0.024,0.018),术后3mo差异无统计学意义(P=0.206)。 FL评分:两组术后1wk;1,2,3mo 差异有统计学意义( P=0.022,0.015,0.036,0.041)。<br> 结论:飞秒激光制瓣LASIK术后泪膜功能的影响男性小于女性。