Malignant melanoma in the pediatric population

• 作者: Aaron Gruman Ali Antar Alyssa Benjamin Anna Stamas Bridget Budny Douglas Reintgen Eric Reintgen Jeff Smith John Psaltis Leah Alvin Mark Giori Michael Reintgen Rosemary Giuliano Taylor Gianangelo
• 来源期刊: 世界外科手术杂志
• 学科: 医学
• 关键词: Pediatric PIGMENTED skin LESIONS SENTINEL LYMPH node BIOPSY MELANOMA
• 年，卷（期）: sjwksszz_2015,（3）
• 页码范围: 229-234
• 页数: 6页
• 分类号: R

摘要

Controversial pigmented lesions in children are a problem for pathologist,clinicians and families that are confronted with this dilemma.Some skin lesions in this population defy diagnosis with pathologists split between a benign diagnosis and a cancer diagnosis.Three cases of controversial pigmented lesions in the pediatric population are presented.Three patients underwent radical resection of the controversial pigmented lesion,intra-operative lymphatic mapping and sentinel lymph node(SLN)biopsy.Due to the low morbidity of the SLN procedure a case is made to perform lymphatic mapping in this clinical scenario.If the SLNs are negative,not much is lost except for the scar and this becomes another line of evidence that perhaps the original lesion was benign.If the SLN shows metastatic cells,then the original skin lesion must be malignant and the patient is offered stageⅢrecommendations that would include complete node dissections and adjuvant Interferon therapy.This strategy provides for adequate treatment of the worse-case scenario,that the skin lesion is malignant.The cost to the patient is a low morbidity procedure,the SLN biopsy.