Treatment Results of Adjuvant Brachytherapy as Monotherapy in Endometrial Cancer: A Retrospective Study from Faculty of Medicine, Chiang Mai University

• 作者: Cholthicha Thipmate Ekkasit Tharavichitkul Imjai Chitapanarux Pitchayaponne Klunklin Razvan M. Galalae Somvilai Chakrabandhu Sukon Prasitwattanaseree Wimrak Onchan
• 来源期刊: 癌症治疗(英文)
• 学科: 医学
• 关键词: ENDOMETRIAL Cancer ADJUVANT BRACHYTHERAPY MONOTHERAPY
• 年，卷（期）: azzlyw_2015,（1）
• 页码范围: 34-39
• 页数: 6页
• 分类号: R73

摘要

Purpose: To report the retrospective study of using intravaginal brachytherapy as adjuvant monotherapy for endometrial cancer. Materials and Methods: From 2001-2009, 47 patients who received completely surgical staging for endometrial carcinoma and were designed by multidisciplinary team were enrolled. All patients received intravaginal brachytherapy (IVBT) with the dose of 5.5 - 7 Gy in 2 - 6 fractions. The treatment results and late toxicities were evaluated and recorded. Results: At the median follow-up time of 44 months, the local control, disease-free survival, metastasis-free survival and overall survival rates were 100%, 97.9%, 97.9% and, 97.9%, respectively. Only age showed the statistical significance with the p-value of 0.046. Two patients (4.3%) developed late genitourinary toxicity. Conclusion: The using of adjuvant IVBT as monotherapy for endometrial carcinoma is feasible.