The Effective Catalyst (Cobalt Salt/Lewis Acid) for Beckmann Rearrangement of Cycloalkanone Oximes to Lactams under Mild Conditions

• 作者: Ayana Ozaki Hidetoshi Yamamoto Keita Hayashi Kenji Hori Masahiro Komeda Michinori Sumimoto Tsunemi Sugimoto
• 来源期刊: 有机化学国际期刊(英文)
• 学科: 化学
• 关键词: Beckmann REARRANGEMENT Cycloalkanone OXIMES LACTAM Cobalt Catalysts LEWIS Acids
• 年，卷（期）: 2015,（2）
• 页码范围: 57-62
• 页数: 6页
• 分类号: O6

摘要

The Beckmann rearrangement of cyclohexanone oxime was achieved by the combined use of cobalt salt and Lewis acids co-catalysts (each 10 mol%). Various combinations of cobalt salts and Lewis acids gave lactams in a satisfactory yield under mild conditions. This method makes it possible to reduce undesirable byproducts.