FeCl<sub>3</sub>Catalyzed One Pot Synthesis of 1-Substituted 1H-1,2,3,4-Tetrazoles under Solvent-Free Conditions

• 作者: Fatemeh Darvish Shima Khazraee
• 来源期刊: 有机化学国际期刊(英文)
• 学科: 化学
• 关键词: Iron(III) Chloride 1-Substituted-1H-1 2 3 4-Tetrazoles Amines Triethyl Orthoformate Solvent-Free TRIMETHYLSILYL AZIDE
• 年，卷（期）: 2015,（2）
• 页码范围: 75-80
• 页数: 6页
• 分类号: O6

摘要

An efficient procedure for the preparation of 1-substituted-1H-1,2,3,4-tetrazoles via a three-component condensation of triethyl orthoformate, amine, and trimethylsilyl azide using inexpensive and environment-friendly FeCl3 as catalyst under solvent-free conditions has been reported. The reaction generates the corresponding 1-substituted tetrazole in excellent yields.