Neoadjuvant or adjuvant therapy for gastric cancer

• 作者: Laurent Quéro Sophie Guillerm Christophe Hennequin.
• 来源期刊: 世界胃肠肿瘤学杂志：英文版（电子版）
• 学科: 医学
• 关键词: RADIOTHERAPY CHEMOTHERAPY REVIEW GASTRIC cancer
• 年，卷（期）: 2015,（8）
• 页码范围: 102-110
• 页数: 9页
• 分类号: R

摘要

Currently, there is no international consensus on thebest treatment regimen for patients with advancedresectablegastric carcinoma. In the United States,where a limited lymph-node dissection is frequentlyperformed, adjuvant chemoradiotherapy after surgery is the standard treatment. In Europe, intensifiedperioperative chemotherapy is commonly administered.In Japan and South Korea, postoperative S-1-based adjuvantchemotherapy after surgery with D2 lymph-nodedissection is the standard treatment. Several ongoingtrials are currently evaluating the optimal sequence ofchemotherapy, radiotherapy, and surgery, as well as theplace of targeted therapeutic agents in the treatment ofadvanced gastric carcinoma.