Adjuvant External Beam Radiotherapy ±Brachytherapy in Endometrial Cancer: A Retrospective Study from Faculty of Medicine, Chiang Mai University

• 作者: Cholthicha Thipmate Ekkasit Tharavichitkul Imjai Chitapanarux Patrinee Traisathit Pitchayaponne Klunklin Razvan M. Galalae Somvilai Chakrabandhu Sukon Prasitwattanaseree Wimrak Onchan
• 来源期刊: 癌症治疗(英文)
• 学科: 医学
• 关键词: ENDOMETRIAL Cancer ADJUVANT Treatment External Beam RADIOTHERAPY
• 年，卷（期）: 2015,（2）
• 页码范围: 115-121
• 页数: 7页
• 分类号: R73

摘要

Purpose: To report the retrospective study of external beam radiotherapy (EBRT) ± intravaginal brachytherapy (IVBT) as adjuvant treatment for endometrial cancer. Materials and Methods: From 2001-2009, 152 patients received complete surgical staging for endometrial carcinoma and were designed by a multidisciplinary team to receive EBRT ± IVBT. The treatment results and late toxicities were evaluated and recorded. Results: At the median follow-up time of 43 months, the disease-free survival, metastasis-free survival and overall survival rates were 96.9%, 96.9% and 96.9%, respectively. Stage and age showed the statistical significance with the p-value of less than 0.001. From five to ten percent of patients developed Grades 1-2 late gastrointestinal and genitourinary toxicities, respectively. Conclusion: The using of adjuvant EBRT ± IVBT for endometrial?carcinoma yielded treatment results and acceptable toxicities.