Cancers in Children Ages 8 to 12 Are Injury-Related

• 作者: Kirsten H. Walen
• 来源期刊: 癌症治疗(英文)
• 学科: 医学
• 关键词: ENDOMITOSIS Endotetraploidization Diplochromosomes REDUCTIVE Division Genomic Change PROLIFERATIVE ADVANTAGE Wound HEALING
• 年，卷（期）: 2015,（2）
• 页码范围: 177-181
• 页数: 5页
• 分类号: R73

摘要

Cancers in young children in early growing age was a short PBS (KQED) report (11/21/2014), but without informational source, which prompted a Google search. Sports-associated injuries with medical healing treatments concluded that there were no association between these body traumas and cancer development. But there are other activities from young children, such as “dare-devil” skateboard and bicycling meter-high jumping with potential high energy falls, to serious broken-bone injuries. Falls of children are among the most common causes of US emergency response. The question is why bodily injury is associated with cancer-development? An answer to this question was exemplified by osteosarcoma in young children, which suggested that injury to growing points of bone and surrounding soft tissue cells would elicit a repair process (wound healing process) producing polyploidy with diplochromosomes. The non-mitotic reductive division of such 4-chromatid chromosomes has been shown?in vitro?to produce pathological cancer-like phenotypes, including gain of a proliferative advantage.