BCG Infection after Bladder Cancer Treatment—3 Clinical Case Reports

• 作者: Angélica Ramos António Sarmento Jo?o Tiago Guimar?es Joana Alves Susana Silva Teresa Carvalho
• 来源期刊: 传染病进展(英文)
• 学科: 医学
• 关键词: Bacillus Calmette-Guérin INTRAVESICAL BCG Therapy BCG INFECTION DISSEMINATED M. BOVIS BCG INFECTION
• 年，卷（期）: 2015,（4）
• 页码范围: 218-221
• 页数: 4页
• 分类号: R73

摘要

Immunotherapy with Bacillus Calmette-Guérin (BCG) to treat non-muscle invasive bladder cancer has become an effective and superior alternative to chemotherapy. Intravesical treatment with BCG appears to be relatively safe;however, occasionally BCG infection complicates such treatment. In the present work we describe three patients in whom BCG infection occurred after intravesical BCG therapy. All patients had positive urine culture forMycobacterium tuberculosis complex, using AccuProbe culture identification and then Genotype Mycobacterium MTBC test identified Mycobacterium bovis BCG. The diagnosis is difficult and microbiologic study is usually negative, so high index of suspicion is essential.