As a typical alluvial-proluvial fan area in the Qaidam Basin, Nuomuhong is important to the research on paleoclimate reconstruction in proluvial fan areas and basin climate change and ecological protection. This paper analyzes features of 2H, 3H, 18 O and 14 C isotopes in Nuomuhong and reconstructs paleoclimate in this area. According to the results: since 28 ka B.P., the ground average temperature decreases and then increases in the Qaidam watershed, reaching the lowest in 17.7 ka B.P. before increasing gradually. In the past 30 000 years, average temperature has changed ranged from 1 ℃ to 5 ℃ in this area; the lowest temperature was different from today’s temperature only by 3 ℃. This shows that climate conditions and natural environment in this area have been relatively stable in the past 30 000 years.