Updates in advanced diffusion-weighted magnetic resonance imaging techniques in the evaluation of prostate cancer

• 作者: Edward Malnor Lawrence Evis Sala Hebert Alberto Vargas Yousef Mazaheri
• 来源期刊: 世界放射学杂志：英文版（电子版）
• 学科: 医学
• 关键词: PERFUSION GLEASON ANATOMICAL APPARENT deviation representing proven EXPONENTIAL ongoing qualitative
• 年，卷（期）: 2015,（8）
• 页码范围: 184-188
• 页数: 5页
• 分类号: R

摘要

Diffusion-weighted magnetic resonance imaging(DWMRI) is considered part of the standard imaging protocol for the evaluation of patients with prostate cancer.It has been proven valuable as a functional tool for qualitative and quantitative analysis of prostate cancer beyond anatomical MRI sequences such as T2-weighted imaging. This review discusses ongoing controversies in DW-MRI acquisition, including the optimal number of b-values to be used for prostate DWI, and summarizes the current literature on the use of advanced DWMRI techniques. These include intravoxel incoherent motion imaging, which better accounts for the nonmono-exponential behavior of the apparent diffusion coefficient as a function of b-value and the influence of perfusion at low b-values. Another technique is diffusion kurtosis imaging(DKI). Metrics from DKI reflect excess kurtosis of tissues, representing its deviation from Gaussian diffusion behavior. Preliminary results suggest that DKI findings may have more value than findings from conventional DW-MRI for the assessment of prostate cancer.