Generation of gene-target dogs using CRISPR/Cas9 system

• 来源期刊: 分子细胞生物学报（英文版）
• 年，卷（期）: 2015,（6）
• 页码范围: 580-583
• 页数: 4页
• 语种: 中文
• DOI: 10.1093/jmcb/mjv061

摘要

Dear Editor, Dogs (Canis familiaris) serve as human companions and are raised to herd livestock, aid hunters, guard homes, perform police and rescue work, and guide the blind.Dogs exhibit close similarities to humans in terms of metabolic, physiological, and anatomical characteristics, and thus are ideal genetic and clinical models to study human diseases (Tsai et al., 2007).Gene target technology is a powerful tool to create new strains of animals with favorable traits.