A Microarray Analysis of Parkinson’s Disease: New Clues and Evaluation

• 作者: Lirong Huo Xiaomin Wang Xibin Liang Yi He
• 来源期刊: 生物科学与医学(英文)
• 学科: 医学
• 关键词: Parkinson’s Disease 6-OHDA MICROARRAY Discrete Genes Cortex STRIATUM
• 年，卷（期）: 2015,（9）
• 页码范围: 55-60
• 页数: 6页
• 分类号: R73

摘要

Parkinson’s disease (PD) is complex and most likely results from an unknown combination of genetic and environmental factors. Here, we defined discrete genes (DGs) in a microarray analysis and found that the percentage of DGs versus all analyzable genes correlated with PD progression. Furthermore, this new parameter was also easily used to evaluate the therapeutic effect of high- frequency electro-acupuncture (EA), thus improving symptoms of PD model rats.