Polyp detection rates using magnification with narrow bandimaging and white light

• 作者: Francisco C Ramirez. James D Panetta Michele A Young Nooman Gilani Sally Stipho Sorin Petre
• 来源期刊: 世界胃肠内镜杂志：英文版（电子版）
• 学科: 医学
• 关键词: COLONOSCOPY NARROW BAND IMAGING Highdefinition MAGNIFICATION Screening YIELD
• 年，卷（期）: 2015,（5）
• 页码范围: 555-562
• 页数: 8页
• 分类号: R

摘要

AIM To compare the yield of adenomas betweennarrow band imaging and white light when using highdefinition/magnification.METHODS： This prospective, non-randomized comparativestudy was performed at the endoscopy unit ofveteran affairs medical center in Phoenix, Arizona.Consecutive patients undergoing first average riskcolorectal cancer screening colonoscopy were selected.Two experienced gastroenterologists performed all theprocedures that were blinded to each other＇s findings.Demographic details were recorded. Data are presentedas mean ± SEM. Proportional data were comparedusing the χ 2 test and means were compared using theStudent＇s t test. Tandem colonoscopy was performedin a sequential and segmental fashion using one of 3strategies： white light followed by narrow band imaging[Group A： white light （WL） → narrow band imaging（NBI）]; narrow band imaging followed by white light（Group B： NBI → WL） and, white light followed by whitelight （Group C： WL → WL）. Detection rate of missedpolyps and adenomas were evaluated in all threegroups.RESULTS： Three hundred patients were studied（100 in each Group）. Although the total time for thecolonoscopy was similar in the 3 groups （23.8 ± 0.7,22.2 ± 0.5 and 24.1 ± 0.7 min for Groups A, B and C,respectively）, it reached statistical significance betweenGroups B and C （P 〈 0.05）. The cecal intubation timein Groups B and C was longer than for Group A （6.5± 0.4 min and 6.5 ± 0.4 min vs 4.9 ± 0.3 min; P 〈0.05）. The withdrawal time for Groups A and C waslonger than Group B （18.9 ± 0.7 min and 17.6 ± 0.6 min vs 15.7 ± 0.4 min; P 〈 0.05）. Overall miss rate forpolyps and adenomas detected in three groups duringthe second look was 18% and 17%, respectively （P= NS）. Detection rate for polyps and adenomas afterfirst look with white light was similar irrespective of thelight used during the second look （WL → WL： 13.7%for polyps, 12.6% for adenomas; WL → NBI： 14.2%for polyps, 11.3% for adenomas）. Miss rate o