“Pyridopyridazine”: A Versatile Nucleus in Pharmaceutical Field

• 作者: Ahmed H. Elmenoufy Alaa Moawad Mohamed A. Ibrahim Mohamed Elagawany Mohammed M. Ghoneim
• 来源期刊: 生物科学与医学(英文)
• 学科: 化学
• 关键词: Pyridopyridazine Pyridopyridazinone AZAHETEROCYCLES Miretilan
• 年，卷（期）: 2015,（10）
• 页码范围: 59-66
• 页数: 8页
• 分类号: O6

摘要

Pyridopyridazines are an important kind of nitrogen atom containing heterocyclic compounds due to their synthetic and pharmacological versatility. This fused heterocycle system represents a common structural feature for many bioactive compounds showing a variety of pharmacological activities which makes it an attractive scaffold for the design and development of new drugs. This mini review summarizes an updated information described in recent literature, about the most relevant pharmacological properties of pyridopyridazines derivatives.